Hypopigmentation is the lack or loss of skin colour.

There are three main types of hypopigmentation, including vitiligo, albinism, and the loss of pigmentation due to skin injury or damage. These are most often permanent, but in some cases they can be treated or even cured. Hypopigmentation can also be caused by an illness.

Hypopigmentation affects Caucasians most often, but can occur in any race. Individuals with the disorder often have very light red or blonde hair, and light blue or gray eyes. However, individuals with albinism will have no pigment in their hair, skin, and eyes, resulting in a very pale appearance, almost white colored hair, and pink skin and eyes.